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The Hidden Skin Warning Sign of High Blood Sugar You Shouldn’t Ignore

Acanthosis Nigricans in armpit. Courtesy: Wikipedia
Acanthosis Nigricans in armpit. Courtesy: Wikipedia

When we think of diabetes, we often focus on the classic symptoms — excessive thirst, frequent urination, fatigue. But did you know that one of the earliest red flags for high blood sugar may actually appear on your skin?


Recently, doctors have raised awareness about a skin condition called acanthosis nigricans — dark, velvety patches of skin — that may indicate persistently high insulin levels and insulin resistance, which are linked to prediabetes or type 2 diabetes. (The Independent)


Let’s explore what this skin sign means, how to recognize it, and what steps you can take if you see it.


What Is Acanthosis Nigricans? A Signal from Your Skin

  • Appearance & location: Acanthosis nigricans shows up as thickened, dark patches (often velvety in texture). These patches are most commonly found on the back of the neck, armpits, groin, under the breasts, or in skin folds. (The Independent)

  • Underlying mechanism: Elevated insulin (a hallmark of insulin resistance) may overstimulate certain skin cells (melanocytes, keratinocytes), increasing production of melanin and keratin, which leads to the darker, thickened skin. (The Independent)

  • Not always diabetes — but a warning: While it doesn’t necessarily mean you already have diabetes, acanthosis nigricans is often associated with metabolic issues, particularly insulin resistance and prediabetes. (The Independent)

Because this is a visible early sign, it can serve as a powerful wake-up call to evaluate your metabolic health before more serious symptoms appear.


Other Common Signs & Symptoms of High Blood Sugar

While acanthosis nigricans deserves more spotlight, it usually doesn’t appear in isolation. Here are classic symptoms to watch for, many of which overlap with hyperglycemia (high blood sugar) and early diabetes:

Symptom

What’s happening in your body

Source / Notes

Excessive thirst & dry mouth

Your kidneys pull water from tissues to help flush excess glucose

Frequent urination (especially at night)

Your kidneys are working overtime to rid your body of extra sugar

Fatigue / low energy

Glucose isn’t entering your cells for energy

Blurred vision

Fluid shifts in the eye from high glucose levels

Unexplained weight loss

Without efficient insulin activity, your body may break down fat and muscle for fuel

Slow-healing wounds and frequent infections

High glucose can impair circulation, immune response, and tissue repair

Itching, skin infections, or recurring fungal infections

Sugar-rich environments fuel microbial growth

Tingling or numbness in hands/feet

Nerve damage (neuropathy) from long-term high blood sugar

Because many of these symptoms develop gradually, it’s possible to dismiss mild versions of them or not even notice the change. That’s why visible skin changes like acanthosis nigricans can be so valuable — they may prompt action before other symptoms fully surface.


Why Early Detection Matters (Prediabetes & Remission)


  • According to U.S. statistics, many adults have undiagnosed diabetes or prediabetes. (The Independent)

  • Prediabetes, when blood sugar is elevated but not yet in the diabetic range, often presents with few or subtle symptoms. But it is reversible with timely lifestyle changes (diet, physical activity, weight loss). (The Independent)

  • For those already diagnosed with type 2 diabetes, the term remission is preferred over “cure.” Remission means blood sugars stay in a non-diabetic range for months without the need for glucose-lowering meds — though vigilant follow-up is still essential. (The Independent)

In short: the earlier you detect metabolic dysregulation, the better your chances of halting progression or even reversing course.


What to Do If You Notice Darkened Skin (or Other Symptoms)


  1. Consult your healthcare provider if you notice skin changes like acanthosis nigricans, or any combination of the symptoms above, let your provider know. Labs such as fasting glucose, HbA1c, or an oral glucose tolerance test can help assess where your blood sugar levels stand.

  2. Lifestyle adjustments are your first line of defense

    • Improve diet quality: Emphasize whole foods, lean proteins, fiber, vegetables, and minimize refined sugars and processed carbs.

    • Move regularly: Moderate aerobic activity and resistance training improve insulin sensitivity.

    • Manage weight: Even modest weight loss (5–10%) can have a significant positive effect on blood sugar.

    • Improve sleep & reduce stress: Both poor sleep and chronic stress can worsen insulin resistance.

  3. Track progress & skin changes

    • Monitor your labs periodically as advised.

    • Photograph and measure affected skin areas over time (with your provider’s guidance). Improvement in acanthosis nigricans may be a helpful visual marker that your metabolic health is improving.

  4. Stay in medical follow-up even if your labs come back normal, regular check-ups are wise, especially if you carry risk factors (family history, overweight, sedentary lifestyle). Prediabetes can remain silent until later stages.


The Takeaway: Your Skin May Be Saying Something Important


While many people associate high blood sugar with thirst, fatigue, or weight changes, skin signs like acanthosis nigricans deserve attention too. If you see darkened, velvety patches in the neck, armpits, groin, or other folds — especially when combined with even mild symptoms — it’s worth investigating.


Because early detection offers your best chance at preventing progression, paying attention to these skin clues can be a key part of proactive metabolic health.


About Direct Diabetes

Direct Diabetes has been helping people with diabetes for nearly 30 years by mailing the supplies they need directly to their home, and helping them avoid the hassle of having to go to a pharmacy. From Continuous Glucose Monitors (CGMs) to insulin pumps and testing supplies, our goal is to take the stress out of managing diabetes so patients can focus on living healthier, fuller lives. We work directly with doctors and insurance companies to make the process simple and affordable.


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This content is for informational purposes only and should not be taken as medical advice. Always consult a qualified healthcare provider about any questions or concerns regarding your health or treatment options.

 
 

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